[BioSB] CD20 – MMab

[BioSB] CD20 – MMab

Catalog No.	Antibody Type	Dilution	Volume/QTY
BSB 5190	Prediluted	Ready-To-Use	3.0 ml
BSB 5191	Prediluted	Ready-To-Use	7.0 ml
BSB 5192	Prediluted	Ready-To-Use	15.0 ml
BSB 5193	Concentrated	1:250-1:1000	0.1 ml
BSB 5194	Concentrated	1:250-1:1000	0.5 ml
BSB 5195	Concentrated	1:250-1:1000	1.0 ml
BSB 5196	Control Slides	5

Intended Use	For In Vitro Diagnostic Use
Summary and Explanation	CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors and mature B-cells, but lost following differentiation into plasma cells. This antibody does not cross-react with non-hematopoietic neoplasms. CD20 (B-cell Pan) reacts with a membrane antigen present in B-cells.CD20 antibody strongly recognizes Reed-Sternberg cells predominant in Hodgkin’s disease. Since no staining of histiocytes or plasma cells has been observed and CD20 antibody has not been detected in T-cell malignancies, it is a very strong marker of B-cell Lymphomas. B-cell Panmarker recognizes a formalin-resistant intracytoplasmic antigen.
Antibody Type	Mouse Monoclonal	Clone	L26
Isotype	IgG2a/K	Reactivity	Paraffin, Frozen
Localization	Membranous	Control	Tonsil, Lymph Node
Presentation	CD20 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.